Oportunități de valorificare a unor produse naturale separate din resurse secundare prin procesul de biorafinare, Cod PN-III-P1-1.1-PD-2016-0892

| Project Title | The valorisation opportunities of natural products, separated from secondary resources throung biorefining process |
| Project Registration Code | PN-III-P1-1.1-PD-2016-0892 |
| Project Acronym | BIOPHENOL |
| Purpose and project planning | The aim of this project is establishing valorisation opportunities of natural products, separated from secondary resources by biorefining process. The biological activity refers to the antioxidant, antibacterial and antifungal activity, as well as to the processes of germination, growth and development of some medicinal plants. Finally we will analyze the chemical composition of the volatile oil obtained from the treated plants. The natural source of polyphenolic compounds is represented from forested waste. For this reason the polyphenolic extracts will be characterized by their total and individual content of polyphenols, tannins and flavonoids. The results will be achieved by: obtaining natural products with antioxidant, antibacterial and antifungal activity or with bioregulators, compatible in the ambient field. |
| Project Start Date | 02 may 2018 |
| Project End Date | 30 april 2020 |
| Project Duration | 24 months |
| Total budget value | 249.974,00 lei |
| Funding | Ministry of Research and Innovation, CNCS-UEFISCDI |
| Team: | TANASE CORNELIU -> PROJECT LEADER MUNTEAN DANIELA-LUCIA -> MENTOR |
| Potential Results | obtaining natural products with antioxidant, antibacterial, antifungal, bioregulator activity, compatible in the ambient field. |
| Conferences | 1. Study of the microwave assisted extraction of polyphenols from beech (Fagus sylvatica L.) bark – scientific paper presented at ”Third International Symposium on Phytochemicals in Medicine and Food” (3-ISPMF), 25 – 30 August, 2018, Kunming, China. 2. Histo-anatomic and physiological aspects of Salvia officinalis L. plants cultivated in the presence of the beech bark extract, scientific paper presented at Scientific Communications Session ”D. Brândză ”, XXV edition, November 8-9, 2019, Bucharest, Romania. 3. The bark of woody vascular plants – a source for bioactive componds, scientific paper presented at ICMPSM 2019: 13. International Conference on Medicinal Plants and Sustainable Medicine, November 11-12, 2019, Tokyo, Japan. |
| Publications | 1. Tanase C., Coșarcă S., Muntean D.L., A Critical Review of Phenolic Compounds Extracted from the Bark of Woody Vascular Plants and Their Potential Biological Activity. Molecules 2019, 24, 1182, F.I. 3,098 (Q2), doi: 103390/molecules24061182. 2. Coșarcă S., Moacă E.A., Tanase C., Muntean D.L., Pavel I.Z., Dehelean C.A., Spruce and beech bark aqueous extracts: source of polyphenols, tannins and antioxidants correlated to in vitro antitumor potential on two diferent cell lines, Wood Science and Technology, 2019, 53, 313–333, FI:1,707 (Q1), doi:10.1007/s00226-018-1071-5 3. Tanase C., Mocan A, Coșarcă S, Gavan A, Nicolescu A, Gheldiu AM, Vodnar DC, Muntean DL, Crișan O. Biological and Chemical Insights of Beech (Fagus sylvatica L.) Bark: A Source of Bioactive Compounds with Functional Properties. Antioxidants (Basel), 2019 Sep 19;8(9). 417, FI: 4,520 (Q1), doi: 10.3390/antiox8090417. 4. Tanase, C.; Nișca, A.; Mirica, A.; Milan, A.; Boz, I. Wood Bark as Valuable Raw Material for Compounds with a Bioregulator Effect in Lemon Balm (Melissa officinalis L.) Plants. Appl. Sci. 2019, 9, 3148, FI: 2,217 (Q2), doi.org/10.3390/app9153148. |
| Host institution | ”George Emil Palade” University of Medicine, Pharmacy, Sciences and Technology of Târgu Mures |
| Scientific reports | 2018 2019 2020 |